Endogenous endophthalmitis secondary to erysipelas

A 64-year-old woman with chronic right arm lymphoedema presented with progressive and painful vision loss in the right eye following diagnosis of erysipelas in the ipsilateral arm. Visual acuity was light perception. Biomicroscopy revealed marked conjunctival injection, decreased corneal transparency and an inflammatory mass in the anterior chamber, which precluded fundoscopy. The ocular ultrasonography features were consistent with acute endophthalmitis, and the patient was admitted to the hospital. A systemic evaluation, including complete physical examination, echocardiography and blood tests, ruled out other sources of infection besides the cutaneous site. Blood cultures were positive for group A Streptococcus. A diagnosis of unilateral acute endophthalmitis due to group A Streptococcus bacteraemia secondary to erysipelas was made and successfully treated with optimal medical care, including prompt intravitreal and systemic antibiotic administration. Despite resolution of the infectious process, visual acuity did not improve.info:eu-repo/semantics/publishedVersio

Myositis ossificans of the quadriceps femoris in a soccer player

A young soccer player was diagnosed with myositis ossificans 6 weeks after a muscle strain in the right thigh. Radiographic and sonographic investigations initially helped to confirm diagnosis and later supported clinical improvement. We present our approach to the case and discuss pathophysiology, prevention and treatment of this rare condition

Sequential Morphological Changes in the CNV Net after Intravitreal Anti-VEGF Evaluated with OCT Angiography

PURPOSE: To assess and describe sequential morphological changes in the choroidal neovascularization (CNV) net using optical coherence tomography angiography (OCTA) in patients undergoing treatment with intravitreal antivascular endothelial growth factor (VEGF). METHODS: Prospective cohort study. OCTA was performed sequentially: before (t0), 1 h (t1), 1 week (t2) and 1 month after the injection (t3), using Avanti RTVue XR equipped with the AngioVue® software (Optovue, Calif., USA). All images were classified by two independent graders. RESULTS: Ten eyes of 10 patients, with a mean age of 72.4 ± 10.5 years, were included. CNV morphology was described as tree-like in 5 eyes, glomerular in 1 and fragmented in 4. A fibrovascular capsule surrounding the CNV net was found in 4 eyes and a feeder trunk was noticed in 6. No changes were observed at t1. Loss of peripheral capillaries, vessel fragmentation and decreased vessel density were evident in 8 eyes at t2. The CNV capillary density and the peripheral anastomosis increased in all of these at t3. Two eyes remained unchanged through the whole length of follow-up. CONCLUSIONS: Significant changes in the CNV net can be observable in OCTA at least 1 week after intravitreal anti-VEGF. The safety of frequent examinations may provide a method of gauging treatment effects

Single or Combined Maquet III Osteotomy: Long Term Results

INTRODUCTION: In 1963, based on biomechanics studies, Maquet proposed the advancement of the patellar tendon insertion as a mean of treating patellofemoral pain. The rationale for this procedure was a reduction in the patellofemoral compression force vector by changing the angular relationship between patella tendon and quadriceps tendon. One of the additional procedures, on a malalign knee, was performing a cupuliform osteotomy above the tibial tuberosity (COATT). OBJECTIVES: Evaluating, on a retrospective and comparative trial, the clinical and radiological long-term outcomes of the patients who underwent a single (M) or combined (MC) Maquet III osteotomy, in order to determine if this surgery as or not fulfilled its initially objectives. METHODS: All surgical records of the Service, between 1970 and 1991, were reviewed. We identify 116 cases registered as “M” or “MC” Maquet III osteotomy. A questionnaire as been prepared for collecting data. We evaluated the preoperative complaints, postoperative complications and range of motion recovery time, as well as the postoperative pain absence period. All patients underwent an objective assessment by the Visual Analog Scale (VAS) and the Kujala Patellofemoral Scoring System (KPFSS). A radiological assessment was also made in order to evaluate the arthrosis degree and compartment affected, the Bicondylo-Patellar Angle (BPA) and the Caton-Deschamps Index (CDI). Mann-Whitney, t-Student and Chi-Square tests were applied for statistical evaluation. p <0.05 was considered statistically significant. RESULTS: According to the study criteria, from the 116 selected patients we could review in our clinics 49 Maquet III osteotomies (n= 25 “M” group vs n=24 “MC” group) . On the “M” group, the average age at surgery was 37.6 ±12.0 years and the postoperative follow-up 27.1 ±3.15 years, versus 56,5 ±6,8 years at surgery and a 23,2 ±3,4 postoperative follow up years on the “MC” group. Prior range of motion was accomplished 4.8 ±3.5 months after surgery on the “M” group versus 6,7 ±3,5 months on the “MC” group (p=0,017). About complications, on the “M” group we have 16,0% (n=4) versus 16,6% (n=4) (p=0,763). The “M” group presented40% (n=10) patients who haven’t referred pain until nowadays versus 38,5% (n=5) (p=0,85), and the average period of of pain absence was 20.5 ±5.7 years on the “M” group versus 11,0 ±1,7 (p=0,001). At the COX score, 58,3% (n=14) of the “M” group had good to excellent outcomes versus 53,8% (n=7) (p=0,793). VAS at rest was 1.7 ±0.7, in activity 4.4±3.0 and KPFSS 61.9 ±22.3 points on the “M” group versus 1,1 ±0,3 (p=0,016), 4,3 ±2,0 (p=0,883) and 54,7 ± 16,9 (p=0,364) points on the “MC” group. Radiologically, BPA was 6.3 ±3.9° and CDI 0.9 ±0.1 on the “M” group versus 11,8 ±3,9 (p=0,000) and 0,9 ±0,2 (p=0,99) on the “MC” group. Nowadays, at the“M” group,58,3% (n=14) had a grade I/II of Kellgren&Lawrence at patellofemoral joint and 79,2.% (n=19) at the femorotibial joint versus 53,8% (n=7) (p=0,793) and 46,2% (n=6) (p=0,041). CONCLUSION: With a cut off follow-up period higher than 20 years, the Maquet III group presented58,3% of good to excellent outcomes with patients presenting a majority of low grade osteoarthritic knee. The COATT procedure hasn’t increased the postoperative complications nor worsen the funcional outcomes. On the other side, the femorotibial grade of arthritis was higher on this group

Subacute L5 Paresis Following a Capoeira Presentation

A young female suffered minor low back trauma during a capoeira presentation. She was initially diagnosed with an acute episode of uncomplicated low back and radicular pain. She kept training and competing until developing paresthesia and weakness of the right leg six weeks later. Physical examination revealed sensory and motor deficits compatible with L5 nerve root compression. The MRI revealed an L5-S1 disc extrusion compressing the right L5 nerve root. Nerve root decompression and partial discectomy were performed, and seven months later she was competing without restrictions. We present our approach and discuss possible pathological mechanisms that may explain this unusual presentation.info:eu-repo/semantics/publishedVersio

Púrpura psicógena – recordar una imagen rara

info:eu-repo/semantics/publishedVersio

Long-Term Management of RAP Lesions in Clinical Practice: Treatment Efficacy and Predictors of Functional Improvement

PURPOSE: To evaluate the long-term efficacy of ranibizumab in the treatment of retinal angiomatous proliferation (RAP) and to identify predictors of functional outcome. METHODS: Retrospective case series comprised 79 eyes of 68 consecutive patients with RAP followed up ≥36 months. Primary end-points were best-corrected visual acuity (BCVA) and central macular thickness (CMT) variation at 36 months and at the last visit. RESULTS: Mean follow-up time was 59.8 ± 16.0 months. All eyes were treated with pro re nata ranibizumab, with (n = 33) or without (n = 46) photodynamic therapy (PDT). Stabilization or improvement in BCVA was observed in 50.6% of the patients at 36 months, and in 40.5% at the end of the follow-up, where 20.3% preserved reading vision. A significant decrease in CMT was observed at 36 months (p < 0.001), but not at the end of the follow-up. Geographic atrophy (GA) was present in 59.5% of the eyes at the final visit. Baseline subretinal fluid was associated with better visual outcomes (p = 0.001). Results of combination treatment with intravitreal ranibizumab and PDT did not significantly differ from ranibizumab monotherapy. CONCLUSION: Modest functional outcomes can be expected from the long-term treatment of RAP lesions in clinical practice, most likely due to the advent of GA. Baseline subretinal fluid positively correlated with final BCVA.info:eu-repo/semantics/publishedVersio